A role for glutathione in buffering excess intracellular copper in Streptococcus pyogenes
L. J. Stewart, C.-l. Y. Ong, M. M. Zhang, S. Brouwer, L. McIntyre, M. R. Davies, M. J. Walker, A. G. McEwan, K. J. Waldron, K. Y. Djoko
This study shows that glutathione buffers excess intracellular copper in Streptococcus pyogenes when the Cu export system is overwhelmed, allowing bacterial survival despite copper toxicity.
mBio · Dec 22, 2020Peer-reviewedMicrobiology