Lung extracellular matrix modulates KRT5+ basal cell activity in pulmonary fibrosis
R. J. Hewitt, F. Puttur, D. C. A. Gaboriau, F. Fercoq, M. Fresquet, W. J. Traves, L. L. Yates, S. A. Walker, P. L. Molyneaux, S. V. Kemp, A. G. Nicholson, A. Rice, R. Lennon, L. M. Carlin, A. J. Byrne, , C. M. Lloyd
This study shows that changes in the extracellular matrix in IPF affect KRT5+ basal cell migration and function, contributing to lung fibrosis.
bioRxiv · Dec 16, 2022Cell Biology