Author

A. H. Bedard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Ferrari· 2 shared A. Guilherme· 2 shared E. Whang· 2 shared F. Henriques· 2 shared J. J. Mack· 2 shared J. P. Kennelly· 2 shared M. Kelly· 2 shared M. P. Czech· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

A. Ferrari

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

T cell cholesterol transport is a metabolic checkpoint that links intestinal immune responses to dietary lipid absorption

Y. Gao, J. P. Kennelly, X. Xiao, E. Whang, A. Ferrari, A. H. Bedard, J. J. Mack, A. H. Nguyen, T. Weston, L. F. Uchiyama, M. S. Lee, S. Young, S. J. Bensinger, P. Tontonoz

This study identifies Aster-A as a cholesterol transporter in T cells that regulates immune signaling and metabolic responses by controlling membrane cholesterol levels.

bioRxiv · Mar 8, 2024Physiology

Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake

A. Ferrari, E. Whang, X. Xiao, J. P. Kennelly, B. Romartinez- Alonso, J. J. Mack, T. Weston, K. Chen, Y. Kim, M. Tol, L. Bideyan, A. Nguyen, Y. Gao, L. Cui, A. H. Bedard, , P. Tontonoz

The paper identifies the Aster pathway as critical for dietary cholesterol uptake and shows it can be targeted with a small molecule inhibitor.

bioRxiv · Jul 7, 2023 · PreprintPhysiology

Single Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis

F. Henriques, A. H. Bedard, A. Guilherme, M. Kelly, J. Chi, P. Zhang, L. M. Lifshitz, K. Bellve, L. Rowland, B. Yenilmez, S. Kumar, Y. Wang, J. Luban, L. S. Weinstein, J. D. Lin, , M. P. Czech

This study shows that adipocyte signals can drive iWAT browning through macrophage-like cells, independent of sympathetic nerves.

bioRxiv · May 4, 2020Physiology

Neuronal Modulation of Brown Adipose Activity Through Perturbation of White Adipocyte Lipogenesis

A. Guilherme, D. J. Pedersen, F. Henriques, A. H. Bedard, E. Henchey, M. Kelly, K. Rahmouni, D. A. Morgan, M. P. Czech

This study shows that white adipocyte lipogenesis influences brown adipose thermogenesis through neuronal signaling.

bioRxiv · May 16, 2018Cell Biology