A. Huang

This study shows that PCK1 deficiency increases O-GlcNAcylation and promotes HCC growth under glucose deprivation by enhancing CHK2 activity.

This study shows that training students to write multiple-choice questions results in high-quality questions suitable for summative assessments, comparable to those written by experts.

This study shows that HBV infection enhances the hexosamine biosynthesis pathway, leading to O-GlcNAcylation of SAMHD1, which boosts antiviral immunity against HBV and HIV-1.

This study shows that the SARS-CoV-specific antibody CR3022 binds strongly to 2019-nCoV RBD with a KD of 6.3 nM, while other antibodies targeting the ACE2 site fail to bind, highlighting the importance of RBD differences for cross-reactivity.

This study uses iTRAQ proteomics to analyze the HCC secretome, identifying CA2 as a diagnostic and prognostic biomarker with potential therapeutic implications.

This study shows PRDM3 suppresses pancreatitis and pancreatic tumorigenesis by modulating inflammation and Kras-driven oncogenesis in acinar cells.

This study develops antigen-specific immune decoys (ASIDs) to intercept and exhaust autoimmune cells, preventing disease in a mouse model of multiple sclerosis.

This study shows Spt6 maintains centromeric CENP-A by preventing its loss during transcription, in both Drosophila and human cells.

The paper identifies an NRPS-like enzyme in fungi that catalyzes the reductive conversion of glycine betaine to choline, revealing its role in choline biosynthesis and homeostasis.