Author

A. Hudait

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

G. A. Voth· 3 shared J. H. Hurley· 2 shared A. L. Yokom· 1 shared A. Pak· 1 shared F. Bouamr· 1 shared H.-G. Wang· 1 shared K. Rose· 1 shared N. Tjahjono· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiophysics

G. A. Voth

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Author profile →

3 papers

Recent·Most cited

HIV-1 Capsid Shape, Orientation, and Entropic Elasticity Regulate Translocationinto the Nuclear Pore Complex

A. Hudait, G. A. Voth

This study uses simulations to show that HIV-1 capsid shape, orientation, and elasticity are critical for translocation through the nuclear pore complex.

bioRxiv · Aug 5, 2023Biophysics

Organization of Upstream ESCRT Machinery at the HIV-1 Budding Site

A. Hudait, J. H. Hurley, G. A. Voth

This study uses molecular dynamics simulations to investigate how ESCRT-I and ESCRT-II proteins interact with HIV-1 Gag lattice at the budding site, revealing their role in modulating membrane curvature and enabling scission.

bioRxiv · Sep 13, 2022 · PreprintBiophysics

A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission

T. G. Flower, Y. Takahashi, A. Hudait, K. Rose, N. Tjahjono, A. Pak, A. L. Yokom, X. Liang, H.-G. Wang, F. Bouamr, G. A. Voth, J. H. Hurley

This study determines the structure of human ESCRT-I and shows it forms a helical assembly that scaffolds and mechanically drives membrane scission during HIV-1 budding.

Nature Structural & Molecular Biology · May 18, 2020Peer-reviewedBiophysics