K. Rose

Identification of a novel papillomavirus from a New Zealand fur seal (Arctocephalus forsteri) with oral papilloma-like lesions

The paper identifies a novel papillomavirus, AfPV1, in New Zealand fur seals with oral papilloma-like lesions and detects a novel gammaherpesvirus, AfGHV1, in another individual.

A RAB7A Phosphoswitch Coordinates Rubicon Homology Protein Regulation of PINK1/Parkin-Dependent Mitophagy

This study identifies a RAB7A phosphoswitch regulated by TBK1 that modulates Rubicon and Pacer interactions to control PINK1/Parkin-dependent mitophagy.

Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes

This study shows tau fibrils enter cells via endocytosis, accumulate in lysosomes, cause membrane damage, and nucleate cytosolic tau at lysosomes.

Transcriptional activity mediated by beta-CATENIN and TCF/LEF family members is completely dispensable for survival of multiple human colorectal cancer cell lines

This study shows that beta-CATENIN and TCF/LEF family members are not essential for survival of multiple colorectal cancer cell lines, despite their role in tumor initiation.

Gammaretroviruses, novel viruses and pathogenic bacteria in Australian bats with neurological signs, pneumonia and skin lesions

This study identifies pathogens in Australian bats with neurological signs, pneumonia, and skin lesions using metatranscriptomic sequencing and traditional diagnostics.

In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair

This study reconstitutes the Ca2+-dependent recruitment of the human ESCRT machinery to lysosomal membranes in vitro, identifying ALG-2 as a key mediator of this process.

Animal lifestyle changes acceptable mass limits for attached tags

The paper introduces a method to calculate acceptable tag mass limits for animals based on their movement patterns and athleticism, showing that 3% of body mass is not always sufficient.

Meta-transcriptomic analysis of virus diversity in urban wild birds with paretic disease

The paper identifies novel viruses in urban wild birds with paresis using meta-transcriptomic analysis and finds potential viral causes of neurological and muscular diseases.

Meta-transcriptomic discovery of a divergent circovirus and a chaphamaparvovirus in captive reptiles with proliferative respiratory syndrome

The paper identifies two novel viruses in captive bearded dragons with respiratory disease using meta-transcriptomic sequencing.

A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission

This study determines the structure of human ESCRT-I and shows it forms a helical assembly that scaffolds and mechanically drives membrane scission during HIV-1 budding.

Metagenomic identification of diverse animal hepaciviruses and pegiviruses

The paper identifies novel hepaciviruses and pegiviruses in Australian wildlife and supports virus-host co-divergence through phylogenetic analysis.

Metagenomic discovery and co-infection of diverse wobbly possum disease viruses and novel hepaciviruses in Australian brushtail possums

The paper identifies a new lineage of arteriviruses and a novel hepacivirus in Australian brushtail possums, showing co-infection and genetic divergence from New Zealand strains.

Matryoshka RNA virus 1: a novel RNA virus associated with Plasmodium parasites in human malaria

The paper identifies a novel RNA virus, MaRNAV-1, associated with Plasmodium vivax in humans and mosquitoes, and a related virus in birds infected with Leucocytozoon parasites.

Extensive Diversity of RNA Viruses in Australian Ticks

This study identifies 19 novel RNA viruses in Australian ticks, including some potentially capable of infecting mammals, and finds no evidence of Borrelia burgdorferi s.l., the causative agent of Lyme disease.