Author

F. Bouamr

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:non-human primate· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

K. McNally· 2 shared S. Best· 2 shared S. Robertson· 2 shared V. Hirsch· 2 shared A. Chiramel· 1 shared A. Hudait· 1 shared A. I. Chiramel· 1 shared A. L. Yokom· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

K. McNally

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Human ESCRT-I and ALIX function as scaffolding helical filaments in vivo

S. J. Spada, K. M. Rose, P. Sette, S. K. O'Connor, V. B. Dussupt, V. S. Yerramilli, K. Nagashima, V. Helle Sjoelund, P. Cruz, J. Kabat, M. Smelkinson, S. Ganesan, A. Nita-Lazar, S. Scarlata, V. Hirsch, , F. Bouamr

This study shows ESCRT-I and ALIX form helical filaments in vivo, serving as structural scaffolds and ESCRT-III assembly templates for membrane scission and viral budding.

bioRxiv · May 1, 2024 · PreprintCell Biology

A pigtailed macaque model for Kyasanur Forest disease virus and Alkhurma hemorrhagic disease virus

R. Broeckel, F. Feldmann, K. McNally, A. Chiramel, P. Hanley, J. Lovaglio, R. Rosenke, D. Scott, G. Saturday, F. Bouamr, S. Robertson, S. Best

This paper establishes a pigtailed macaque model for KFDV and AHFV that replicates human disease symptoms and viral tropism.

bioRxiv · Jun 1, 2021Microbiology

A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission

T. G. Flower, Y. Takahashi, A. Hudait, K. Rose, N. Tjahjono, A. Pak, A. L. Yokom, X. Liang, H.-G. Wang, F. Bouamr, G. A. Voth, J. H. Hurley

This study determines the structure of human ESCRT-I and shows it forms a helical assembly that scaffolds and mechanically drives membrane scission during HIV-1 budding.

Nature Structural & Molecular Biology · May 18, 2020Peer-reviewedBiophysics

TRIM5α restricts flavivirus replication by targeting the viral protease for proteasomal degradation.

A. I. Chiramel, N. Meyerson, K. McNally, R. M. Broeckel, V. Montoya, O. Mendes-Solis, S. Robertson, G. Sturdevant, K. Lubick, V. Nair, B. Youseff, R. Ireland, C. Bosio, K. Kim, J. Luban, , S. M. Best

This study shows TRIM5α restricts flavivirus replication by targeting the viral protease for proteasomal degradation, with implications for human susceptibility to emerging flaviviruses.

bioRxiv · Apr 11, 2019Microbiology