Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
36 papers
Recent·Most cited
M. Hauge Pedersen, J. Pham, H. Mancebo…·J. A. Javitch
This paper introduces a luminescence-based assay to measure arrestin recruitment to unmodified GPCRs, avoiding C-terminal modifications.
N. Caengprasath, N. Gonzalez-Abuin, M. Shchepinova…·A. Hanyaloglu
This study shows propionate activates endosomal Gi/p38 signaling via FFA2 to induce GLP-1 release in enteroendocrine cells.
J. S. Smith, T. F. Pack, A. Inoue…·S. Rajagopal
The paper demonstrates that Gαi proteins can form complexes with β-arrestin, independent of their canonical G protein coupling, and these complexes can bind GPCRs and ERK.
T. Buenaventura, W. E. Laughlin, S. Bitsi…·A. Tomas
This study shows that agonist binding affinity affects GLP-1R palmitoylation, nanodomain clustering, and signaling in pancreatic beta cells, influencing insulin secretion.
C. Nagiri, W. Shihoya, A. Inoue…·O. Nureki
The paper reports the crystal structure of the human ETB receptor complexed with the inverse agonist IRL2500, revealing its binding mechanism and ETB-selectivity.
Y. Hisano, M. Kono, E. Engelbrecht…·T. Hla
The paper identifies LPAR1-induced S1PR1/β-arrestin coupling as a mechanism regulating lymphatic endothelial junctional architecture in murine lymph nodes.