Author

A. J. Ridley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

D. P. Dyer· 2 shared N. Pun· 2 shared R. Karlsson· 2 shared R. L. Miller· 2 shared T. A. Jowitt· 2 shared A. L. Gray· 1 shared A. R. Roberts· 1 shared C. Hughes· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

D. P. Dyer

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Author profile →

2 papers

Recent·Most cited

Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans

A. J. Ridley, Y. Ou, R. Karlsson, N. Pun, H. L. Birchenough, T. A. Jowitt, C. Lawless, R. L. Miller, D. P. Dyer

The paper analyzes chemokine gene expression across species, tissues, and diseases, showing complex patterns and demonstrates that ECM proteoglycans modulate chemokine signaling and leukocyte recruitment.

bioRxiv · Sep 20, 2022Immunology

Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate wide-spread non-receptor mediated immune cell recruitment

A. L. Gray, R. Karlsson, A. R. Roberts, A. J. Ridley, N. Pun, C. Hughes, L. Medina-Ruiz, H. Birchenough, C. Salanga, E. A. Yates, J. E. Turnbull, T. M. Handel, G. Graham, T. A. Jowitt, I. Schiessl, , D. P. Dyer

The paper shows CXCL4 binds to extracellular matrix proteoglycans, increasing vascular permeability and recruiting various leukocytes through a non-canonical mechanism.

bioRxiv · Jul 10, 2022 · PreprintImmunology