Author

C. Salanga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

I. Kufareva· 2 shared L. Borrega-Roman· 2 shared S. Gu· 2 shared T. M. Handel· 2 shared A. J. Ridley· 1 shared A. J. Tebben· 1 shared A. L. Gray· 1 shared A. Lona· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

I. Kufareva

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular determinants of antagonist interactions with chemokine receptors CCR2 and CCR5

J. R. D. Dawson, G. M. Wadman, P. Zhang, A. J. Tebben, P. H. Carter, S. Gu, T. Shroka, L. Borrega-Roman, C. Salanga, T. M. Handel, I. Kufareva

This study identifies molecular determinants of CCR2 and CCR5 antagonist interactions using docking and AI screening, revealing structural principles and selectivity mechanisms.

bioRxiv · Nov 15, 2023 · PreprintPharmacology & Toxicology

Ligand-Dependent Mechanisms of C-C Chemokine Receptor 5 (CCR5) Trafficking Revealed by APEX2 Proximity Labeling Proteomics

S. Gu, S. Maurya, A. Lona, L. Borrega-Roman, C. Salanga, D. J. Gonzalez, I. Kufareva, T. Handel

This study uses APEX2 proximity labeling and mass spectrometry to uncover ligand-dependent CCR5 trafficking mechanisms, revealing distinct internalization and degradation pathways.

bioRxiv · Nov 1, 2023 · PreprintCell Biology

Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate wide-spread non-receptor mediated immune cell recruitment

A. L. Gray, R. Karlsson, A. R. Roberts, A. J. Ridley, N. Pun, C. Hughes, L. Medina-Ruiz, H. Birchenough, C. Salanga, E. A. Yates, J. E. Turnbull, T. M. Handel, G. Graham, T. A. Jowitt, I. Schiessl, , D. P. Dyer

The paper shows CXCL4 binds to extracellular matrix proteoglycans, increasing vascular permeability and recruiting various leukocytes through a non-canonical mechanism.

bioRxiv · Jul 10, 2022 · PreprintImmunology