Author

D. P. Dyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

L. Medina-Ruiz· 3 shared A. J. Ridley· 2 shared C. Hughes· 2 shared G. J. Graham· 2 shared H. L. Birchenough· 2 shared N. Pun· 2 shared R. Karlsson· 2 shared R. L. Miller· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

L. Medina-Ruiz

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Author profile →

5 papers

Recent·Most cited

CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signalling

S. P. Giblin, S. Ranawana, S. Hassibi, H. L. Birchenough, K. T. Mincham, R. J. Snelgrove, T. Tsuchiya, S. Kanegasaki, D. P. Dyer, J. E. Pease

This study investigates CXCL17's structural and functional properties, finding it does not act as a chemokine but binds glycosaminoglycans and modulates chemotaxis.

bioRxiv · Jul 7, 2023 · PreprintImmunology

Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans

A. J. Ridley, Y. Ou, R. Karlsson, N. Pun, H. L. Birchenough, T. A. Jowitt, C. Lawless, R. L. Miller, D. P. Dyer

The paper analyzes chemokine gene expression across species, tissues, and diseases, showing complex patterns and demonstrates that ECM proteoglycans modulate chemokine signaling and leukocyte recruitment.

bioRxiv · Sep 20, 2022Immunology

Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate wide-spread non-receptor mediated immune cell recruitment

A. L. Gray, R. Karlsson, A. R. Roberts, A. J. Ridley, N. Pun, C. Hughes, L. Medina-Ruiz, H. Birchenough, C. Salanga, E. A. Yates, J. E. Turnbull, T. M. Handel, G. Graham, T. A. Jowitt, I. Schiessl, , D. P. Dyer

The paper shows CXCL4 binds to extracellular matrix proteoglycans, increasing vascular permeability and recruiting various leukocytes through a non-canonical mechanism.

bioRxiv · Jul 10, 2022 · PreprintImmunology

Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice

L. Medina-Ruiz, R. Bartolini, D. P. Dyer, F. Vidler, C. Hughes, F. Schuette, S. Love, J. Fu, A. F. Stewart, G. J. Graham

This study generates multi-chemokine receptor reporter mice to analyze receptor expression dynamics on myeloid cells, revealing high specificity and selectivity in chemokine receptor expression.

bioRxiv · Aug 11, 2021Immunology

The chemokine receptor CXCR2 contributes to murine adipocyte development

D. P. Dyer, J. Boix Nebot, C. Kelly, L. Medina-Ruiz, F. Scheutte, G. J. Graham

This study shows that CXCR2 deficiency in mice leads to reduced subcutaneous adipose tissue due to smaller adipocytes, primarily in females.

bioRxiv · Jun 5, 2018Immunology