Mechanical regulation of cellular energy metabolism in cancer microenvironments
J. M. Toth, A. Jaganathan, R. Basir, L. Pieuchot, Y. Shen, C. A. Reinhart-King, V. B. Shenoy
The paper develops a model linking matrix stiffness and ligand density to cellular bioenergetics in cancer cells, showing how mechanical forces influence metabolic pathways and contractility.
bioRxiv · Apr 30, 2024 · PreprintBiophysics