Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton
A. E. M. Beedle, A. Jaganathan, A. Albajar-Sigales, F. M. Yavitt, K. Bera, I. Andreu, I. Granero-Moya, D. Zalvidea, Z. M. Kechagia, G. Wiche, X. Trepat, J. Ivaska, K. S. Anseth, V. Shenoy, P. Roca-Cusachs
The paper shows that fibrillar adhesions control nuclear mechanical response timescales through vimentin cytoskeleton anchoring via plectin 1f.
bioRxiv · Nov 8, 2023Biophysics