Author

A. Kuzmin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:protein folding & dynamics· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

I. Gushchin· 3 shared A. Nikolaev· 2 shared A. Remeeva· 2 shared E. Kuznetsova· 2 shared O. Semenov· 2 shared A. A. Mihailova· 1 shared A. Anuchina· 1 shared A. G. Mikhailova· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiophysics

I. Gushchin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Reengineering of a flavin-binding fluorescent protein using ProteinMPNN

A. Nikolaev, A. Kuzmin, E. Markeeva, E. Kuznetsova, O. Semenov, A. Anuchina, A. Remeeva, I. Gushchin

The paper tests ProteinMPNN's ability to reengineer a flavin-binding fluorescent protein, showing it can generate variants with similar properties to the original.

bioRxiv · Aug 25, 2023Bioengineering

Two distinct mechanisms of flavoprotein spectral tuning revealed by low-temperature and time-dependent spectroscopy

A. Nikolaev, E. V. Tropina, K. N. Boldyrev, E. G. Maksimov, V. Borshchevskiy, A. Mishin, A. Yudenko, A. Kuzmin, E. Kuznetsova, O. Semenov, A. Remeeva, I. Gushchin

The paper uses spectroscopy and X-ray structures to reveal two distinct mechanisms by which flavin-binding proteins tune their fluorescence spectra.

bioRxiv · Jul 17, 2023Biophysics

Structure and dynamics of the SARS-CoV-2 envelope protein monomer

A. Kuzmin, P. Orekhov, R. Astashkin, V. Gordeliy, I. Gushchin

This study uses molecular dynamics simulations to analyze the structure and dynamics of the SARS-CoV-2 envelope protein monomer, revealing its membrane orientation and interactions with host factors.

bioRxiv · Mar 10, 2021Biophysics

A>G substitutions on a heavy chain of mitochondrial genome marks an increased level of aerobic metabolism in warm versus cold vertebrates .

A. G. Mikhailova, D. Iliushchenko, V. Shamanskiy, A. A. Mihailova, K. Ushakova, E. Tretiakov, S. Oreshkov, D. Knorre, L. Polishchuk, D. Lawless, A. Kuzmin, S. Denisov, I. Kozenkov, I. Mazunin, W. Kunz, , K. Popadin

The paper examines A>G substitutions in mtDNA across vertebrates, finding higher rates in warm-blooded species, suggesting temperature influences oxidative damage and mutational patterns.

bioRxiv · Jul 25, 2020 · PreprintEvolutionary Biology

IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids

M. Larion, A. Lita, A. Pliss, A. Kuzmin, T. Yamasaki, L. Zhang, T. Dowdy, C. Burks, N. de Val, O. Celiku, V. Ruiz-Rodado, E.-R. Nicoli, M. Kruhlak, T. Andresson, S. Das, , P. N. Prasad

This paper identifies lipid imbalances caused by IDH1 mutations that lead to organelle dysfunction, with therapeutic implications for glioma treatment.

bioRxiv · Mar 20, 2020Cancer Biology