Author

A. L. Garnham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Baldi· 1 shared A. M. Olthof· 1 shared A. P. Ng· 1 shared A. Pettikiriarachchi· 1 shared B. B. Williams· 1 shared C. Bennett· 1 shared C. S. Li-Wai-Suen· 1 shared D. Clucas· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Baldi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Iron homeostasis governs erythroid phenotype in Polycythemia Vera

C. Bennett, V. E. Jackson, A. Pettikiriarachchi, T. Hayman, U. Schaeper, G. Moir-Meyer, K. Fielding, R. Ataide, D. Clucas, A. Baldi, A. L. Garnham, C. S. Li-Wai-Suen, W. S. Alexander, M. Bahlo, K. Burbury, , S.-R. Pasricha

This study links iron homeostasis to Polycythemia Vera by showing HFE mutations affect hepcidin expression, which regulates erythroid phenotype.

bioRxiv · May 3, 2022 · PreprintCancer Biology

The minor spliceosome offers a therapeutically viable target for the treatment of a broad spectrum of cancers

K. Doggett, K. J. Morgan, S. Mieruszynski, B. B. Williams, A. M. Olthof, A. L. Garnham, M. J. G. Milevskiy, L. Whitehead, J. Coates, M. Buchert, R. J. O'Donoghue, T. E. Hall, Z. Gong, T. L. Putoczki, M. Ernst, , J. K. Heath

This study shows that targeting the minor spliceosome, specifically Rnpc3, reduces tumor burden in multiple cancer models and is associated with poor patient survival in cancer transcriptomes.

bioRxiv · Dec 9, 2021Cancer Biology