Author

A. L. Solon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. Ohi· 3 shared A. A. Apfelbaum· 1 shared A. C. Latronico· 1 shared A. I. Nesvizhskii· 1 shared A. M. Lerario· 1 shared A. Wakamatsu· 1 shared B. B. Mendonca· 1 shared B. M. P. Mariani· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

R. Ohi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

β-catenin programs a tissue-specific epigenetic vulnerability in aggressive adrenocortical carcinoma

D. R. Mohan, K. S. Borges, I. Finco, C. R. LaPensee, J. Rege, A. L. Solon, D. W. Little, T. Else, M. Q. Almeida, D. Dang, J. Haggerty-Skeans, A. A. Apfelbaum, M. Vinco, A. Wakamatsu, B. M. P. Mariani, , G. D. Hammer

This study shows that β-catenin maintains adrenocortical carcinoma differentiation through chromatin and histone interactions, and that targeting EZH2 can disrupt this process and inhibit tumor growth.

bioRxiv · Jul 2, 2022 · PreprintCancer Biology

Kinesin-binding protein remodels the kinesin motor to prevent microtubule-binding

A. L. Solon, Z. Tan, K. L. Schutt, L. Jepsen, S. E. Haynes, A. I. Nesvizhskii, D. Sept, J. Stumpff, R. Ohi, M. A. Cianfrocco

This study determines the structural mechanism by which KIFBP remodels kinesin motors to block microtubule-binding, revealing a 2-pronged inhibition strategy.

bioRxiv · Jun 2, 2021Cell Biology

K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15

M. A. Begley, A. L. Solon, E. M. Davis, M. G. Sherrill, R. Ohi, M. W. Elting

This study investigates how Kif15 reinforces k-fiber bundles in the mitotic spindle through microtubule crosslinking, preventing chromosome segregation errors.

bioRxiv · May 19, 2020Cell Biology