Author

A. Larbi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Singhal· 2 shared B. Lee· 2 shared J. Lum· 2 shared A. Andiappan· 1 shared A. Lee· 1 shared A. M. Nguyen· 1 shared A. Tay· 1 shared A. Tizazu· 1 shared

Activity by Year

2020-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

A. Singhal

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4 papers

Recent·Most cited

Proliferative and quiescent human gastric cancer stem-like cells are associated with differential chemoresistance and patient mortality

K. S. Ang, H. K. Lee, M. Chevrier, M. Goh, J. Ling, V. Koh, X. Zhang, J. C. Tan, N. Lee, S. Erdal Irac, Z. M. Lim, J. Lum, A. Tay, C. Antoine Dutertre, C. Tang, , J. Chen

This study identifies two stem-like gastric cancer subpopulations with distinct chemoresistance and survival outcomes using scRNA-seq and organoid models.

bioRxiv · Oct 23, 2020 · PreprintImmunology

Metformin enhances anti-mycobacterial responses by educating immunometabolic circuits of CD8+ T cells

J. Bohme, N. Martinez, S. Li, A. Lee, M. Marzuki, A. Tizazu, D. Ackart, J. Frenkel, A. Todd, E. Lachmandas, J. Lum, F. Shihui, T. P. Ng, B. Lee, A. Larbi, , A. Singhal

This study shows metformin improves anti-mycobacterial responses by enhancing metabolic and functional properties of CD8+ T cells in mice and humans.

bioRxiv · Aug 26, 2020Immunology

A Multi-Phenotype System to Discover Therapies for Age-Related Dysregulation of the Immune Response to Viral Infections

B. W. White, B. Komalo, L. Nicolaisen, M. Donne, C. Marsh, R. M. DeVay, A. M. Nguyen, W. Cousin, J. Heinrich, W. J. Van Trump, T. Plott, C. J. Fuller, D. Nguyen, D. Chen, D. Bucher, , B. Kamens

This paper develops a multi-phenotype system to identify compounds that rejuvenate the immune response in older adults to viral infections, finding disulfiram and triptonide as promising candidates.

bioRxiv · Jul 30, 2020 · PreprintImmunology

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early prognostic marker for severe COVID-19

G. Carissimo, W. Xu, I. Kwok, M. Y. Abdad, Y. H. Chan, S. W. Fong, K. J. Puan, C. Y. P. Lee, N. K.-W. Yeo, S. N. Amrun, R. S.-L. Chee, W. How, S. Chan, E. B. Fan, A. Andiappan, , L. F. Ng

The paper identifies an immature neutrophil-to-VD2 T-cell ratio as a prognostic marker for severe COVID-19 using flow cytometry data.

bioRxiv · Jun 11, 2020Immunology