Author

A. M. Frey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Trost· 3 shared A. Basle· 1 shared A. Dannoura· 1 shared A. J. Vickers· 1 shared A. L. George· 1 shared A. Silale· 1 shared B. B. A. Raymond· 1 shared B. van den Berg· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCancer Biology

M. Trost

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Proteomic Analysis Reveals Trilaciclib-Induced Senescence

M. Hermosilla-Trespaderne, M. X. Hu-Yang, A. Dannoura, A. M. Frey, A. L. George, M. Trost, J. L. Marin-Rubio

This paper uses proteomics to show trilaciclib induces senescence in CML and NSCLC cells by stabilizing CDK4/6 and activating autophagy.

bioRxiv · Mar 12, 2024Cancer Biology

Proteomic mapping of macrophages in response to the clearance of apoptotic cells reveals a unique reprogramming profile.

B. B. A. Raymond, A. M. Frey, M. Trost

This study uses proteomic analysis to reveal reprogramming in macrophages during efferocytosis, showing an alternatively activated phenotype and secretome-driven reprogramming of naive macrophages.

bioRxiv · Nov 23, 2023 · PreprintCell Biology

Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure

S. Stanley, X. Wang, Q. Liu, Y. Y. Kwon, A. M. Frey, N. D. Hicks, A. J. Vickers, S. Hui, S. M. Fortune

This study investigates the evolutionary adaptation of Mycobacterium tuberculosis lactate dehydrogenase (LldD2) under host pressure, showing its role in metabolic flexibility and virulence.

bioRxiv · Oct 9, 2023 · PreprintMicrobiology

BtuB TonB-dependent transporters and BtuG surface lipoproteins form stable complexes for vitamin B12 uptake in gut Bacteroides.

J. Abellon-Ruiz, K. Jana, A. Silale, A. M. Frey, A. Basle, M. Trost, U. Kleinekathofer, B. van den Berg

This study identifies stable complexes between BtuB transporters and BtuG lipoproteins in Bacteroides thetaiotaomicron for vitamin B12 uptake via cryoEM, X-ray crystallography, and MD simulations.

bioRxiv · Nov 17, 2022Microbiology