Author

A. Maraver

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Djiane· 2 shared I. Ferrer· 2 shared J. Colinge· 2 shared L. Heron-Milhavet· 2 shared L. Paz-Ares· 2 shared M. Mancini· 2 shared A. Bellahcene· 1 shared A. Casanova· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. Djiane

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Author profile →

5 papers

Recent·Most cited

MDM2 stabilization of Notch intracellular domain upon DNA damage plays a major role in non-small cell lung carcinoma response to platinum chemotherapy

S. Bernardo, Q. D. Thomas, M. Mancini, A. Santos, S. F. Rasamizafy, A. M. Maacha, A. Giry, e. Bousquet-Mur, L. Papon, M. Goussard, C. Fremin, A. Pasquier, M. Rodriguez, C. Travert, J. L. Pujol, , A. Maraver

This study identifies MDM2 stabilization of NICD in response to platinum chemotherapy in NSCLC, showing that targeting MDM2 and NICD improves survival and reduces tumor growth.

bioRxiv · Apr 29, 2024 · PreprintCancer Biology

RIP140 regulates HES1 oscillatory expression and mitogenic activity in colon cancer cells

N. Sfeir, M. Kajdan, S. Jalaguier, S. Bonnet, C. Teyssier, S. Pyrdziak, R. Yuan, E. Bousquet, A. Maraver, F. Bernex, N. Pirot, F. Boissiere, A. Castet-Nicolas, M. Lapierre, V. Cavailles

This study shows RIP140 regulates HES1 expression and mitogenic activity in colon cancer cells, with implications for patient survival.

bioRxiv · May 13, 2023 · PreprintCancer Biology

Farnesyltransferase inhibition overcomes the adaptive resistance to osimertinib in EGFR-mutant NSCLC

S. Figarol, C. Delahaye, R. Gence, R. Asslan, S. Pagano, C. Tardy, J. Colinge, J.-P. Villemin, A. Maraver, I. Ferrer, L. Paz-Ares, I. Lajoie-Mazenc, E. Clermont, A. Casanova, A. Pradines, , G. Favre

This study identifies early escapers as a rare cell population resistant to EGFR-TKi and shows that tipifarnib overcomes this resistance by targeting Rho/ROCK pathway and preventing relapse.

bioRxiv · Apr 1, 2022 · PreprintCancer Biology

Tumor-Antagonizing Fibroblasts Secrete Prolargin as Tumor Suppressor in Hepatocellular Carcinoma

B. Chiavarina, R. Ronca, Y. Otaka, R. B. Sutton, S. Rezzola, T. Yokobori, P. Chiodelli, R. Souche, A. Maraver, G. Faa, T. Oyama, S. Gofflot, A. Bellahcene, O. Detry, P. Delvenne, , A. Turtoi

The paper identifies prolargin as a tumor suppressor secreted by tumor-antagonizing fibroblasts in HCC, showing its correlation with patient outcomes and its inhibition of tumor progression.

bioRxiv · Jan 4, 2021 · PreprintCancer Biology

MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis

D. Kantar, E. Bousquet Mur, M. Mancini, V. Slaninova, Y. Ben Salah, L. Costa, E. Forest, P. Lassus, C. Geminard, F. Boissiere-Michot, B. Orsetti, C. Theillet, J. Colinge, C. Benistant, A. Maraver, , A. Djiane

The paper shows that MAGI1 loss in luminal breast cancer promotes tumorigenesis by activating the AMOTL2/p38 stress pathway, which is inhibited by MAGI1.

bioRxiv · Jun 13, 2020Cancer Biology