Author

A. P. Drainas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. Sage· 3 shared C. Kong· 2 shared G. L. Coles· 2 shared M. C. Lee· 2 shared M. M. Winslow· 2 shared A. Holzem· 1 shared A. L. He· 1 shared A. M. Pasca· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

J. Sage

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A multiplexed in vivo approach to identify driver genes in small cell lung cancer

M. C. Lee, H. Cai, C. W. Murray, C. Li, Y. T. Shue, L. Andrejka, A. L. He, A. Holzem, A. P. Drainas, J. H. Ko, G. L. Coles, C. Kong, S. Zhu, C. Zhu, J. Wang, , J. Sage

The paper develops a multiplexed in vivo approach to identify driver genes in SCLC using CRISPR/Cas9 and lentiviral barcoding, finding TSC1 as a robust tumor suppressor.

bioRxiv · Mar 28, 2022Cancer Biology

Neuronal mimicry generates an ecosystem critical for brain metastatic growth of SCLC

F. Qu, S. Cao, W. Michno, C. J. Madubata, A. Puno, A. P. Drainas, M. C. Lee, D. Yang, A. Toland, C. Kong, M. Das, M. M. Winslow, A. M. Pasca, J. Sage

This study shows SCLC cells mimic neurons to promote brain metastasis by recruiting astrocytes through factors like Reelin and SERPINE1.

bioRxiv · Aug 10, 2021 · PreprintCancer Biology

Spatial epitope barcoding reveals subclonaltumor patch behaviors

X. Rovira-Clave, A. P. Drainas, S. Jiang, Y. Bai, M. Baron, B. Zhu, M. Markovic, G. L. Coles, M. C. Bassik, J. Sage, G. P. Nolan

The paper develops a method to track subclonal tumor patch behaviors using spatial epitope barcoding and imaging, revealing emergent properties in cancer cell states.

bioRxiv · Jun 29, 2021 · PreprintCancer Biology