Author

A. P. Le

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

B. Ladoux· 3 shared R.-M. Mege· 2 shared Y. Toyama· 2 shared C. T. Lim· 1 shared G. H. N. Sankara Narayana· 1 shared G. Peyret· 1 shared H. E. Balcioglu· 1 shared I. Yow· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

B. Ladoux

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanics defines the spatial pattern of compensatory proliferation

T. Kawaue, I. Yow, A. P. Le, Y. Lou, M. Loberas, M. Shagirov, J. Prost, T. Hiraiwa, B. Ladoux, Y. Toyama

The paper identifies that spatial inhomogeneity in mechanotransduction via YAP drives compensatory proliferation in response to apoptosis.

bioRxiv · Jul 4, 2021 · PreprintCell Biology

Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion

A. P. Le, J.-F. Rupprecht, R.-M. Mege, Y. Toyama, C. T. Lim, B. Ladoux

This study identifies a dual-mode actin mechanism involving lamellipodia protrusions and purse-string contractility that drives apoptotic cell extrusion in epithelia.

bioRxiv · Aug 26, 2020Cell Biology

Force-Dependent Binding Of Vinculin To α-catenin Regulates Cell-Cell Contacts Stability And Collective Cell Behavior

R. Seddiki, G. H. N. Sankara Narayana, P.-O. Strale, H. E. Balcioglu, G. Peyret, M. Yao, A. P. Le, L. C. Teck, J. Yan, B. Ladoux, R.-M. Mege

This study shows that force-dependent vinculin binding to α-catenin stabilizes adherens junctions and regulates cell-cell contact dynamics and collective cell behavior.

bioRxiv · Dec 21, 2017Cell Biology