J.-F. Rupprecht

DARE: Division Axis and Region Estimation from 2D and 3D Time-Lapse Images

The paper introduces a two-stage framework for detecting cell divisions in 2D and 3D time-lapse images using segmentation and regression models, achieving high accuracy with efficient architectures.

E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes.

Alcanivorax borkumensis Biofilms Enhance Oil Degradation By Interfacial Tubulation

A. borkumensis biofilms transition from thick to thin dendritic phenotypes to enhance oil consumption through interfacial tubulation and reduced interfacial tension.

Enhanced cell viscosity: a new phenotype associated withlamin A/C alterations

This study quantifies whole cell mechanical changes caused by lamin A/C alterations using microfluidic experiments, revealing increased long-time viscosity as a potential diagnostic marker.

Two-point optical manipulation reveals mechanosensitive remodeling of cell-cell contacts in vivo

This paper develops an optical manipulation technique to study mechanosensitive remodeling of cell-cell contacts in Drosophila embryos and identifies mechanosensitive feedback mechanisms.

Mechanical stress driven by rigidity sensing governs epithelial stability

The paper shows that substrate stiffness drives mechanical switches in epithelial monolayers, leading to stochastic failure through topological defects.

Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion

This study identifies a dual-mode actin mechanism involving lamellipodia protrusions and purse-string contractility that drives apoptotic cell extrusion in epithelia.

Shaping the zebrafish myotome by differential friction and active stress

This study investigates how differential friction and active stress contribute to the formation of the zebrafish myotome's chevron shape through mechanical coupling and tissue plasticity.