Author

I. Yow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

B. Ladoux· 2 shared J. Prost· 2 shared Y. Toyama· 2 shared A. M. Salazar· 1 shared A. P. Le· 1 shared B. C. Low· 1 shared C. Jebane· 1 shared D. C. P. Wong· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiophysics

B. Ladoux

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Natural Killer cell contractility and cytotoxicity is driven by TLR3 agonist-mediated TAZ cytoplasmic sequestration

D. C. P. Wong, Z. Xia, N. Shao, J. Y. Yeo, T. Thivakar, I. Yow, A. M. Salazar, Y.-C. Liou, B. C. Low, J. L. Ding

This study shows that TLR3 agonist hiltonol sequesters TAZ in NK cells, enhancing cytotoxicity by increasing contractility and reducing inhibitory receptors.

bioRxiv · Jan 18, 2023 · PreprintCell Biology

Mechanical stress driven by rigidity sensing governs epithelial stability

S. Sonam, L. Balasubramaniam, S.-Z. Lin, I. Yow, I. P. Jauma, C. Jebane, M. Karnat, Y. Toyama, P. Marcq, J. Prost, R.-M. Mege, J.-F. Rupprecht, B. Ladoux

The paper shows that substrate stiffness drives mechanical switches in epithelial monolayers, leading to stochastic failure through topological defects.

bioRxiv · Mar 10, 2022Biophysics

Mechanics defines the spatial pattern of compensatory proliferation

T. Kawaue, I. Yow, A. P. Le, Y. Lou, M. Loberas, M. Shagirov, J. Prost, T. Hiraiwa, B. Ladoux, Y. Toyama

The paper identifies that spatial inhomogeneity in mechanotransduction via YAP drives compensatory proliferation in response to apoptosis.

bioRxiv · Jul 4, 2021 · PreprintCell Biology