Author

A. Polesskaya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Assay:proteomics· 2 Organism:zebrafish· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. M. Gautreau· 4 shared S. Romero· 3 shared Y. Wang· 3 shared A. Boutillon· 2 shared A. I. Fokin· 2 shared J. James· 2 shared N. B. David· 2 shared R. Guerois· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersCell Biology

A. M. Gautreau

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4 papers

Recent·Most cited

Vinculin-Arp2/3 Interaction Inhibits Branched Actin Assembly to Control Cell Migration and Cell Cycle Progression

J. James, A. I. Fokin, D. Y. Guschin, H. Wang, A. Polesskaya, S. N. Rubtsova, C. Le Clainche, P. Silberzan, A. M. Gautreau, S. Romero

This study shows that vinculin's interaction with Arp2/3 inhibits branched actin assembly, affecting cell migration and cell cycle progression in mammary epithelial cells.

bioRxiv · Oct 9, 2023 · PreprintCell Biology

Inactivating Negative Regulators of Cortical Branched Actin Enhances Persistence of Single Cell Migration

A. I. Fokin, A. Boutillon, J. James, L. Courtois, S. Vacher, G. Simanov, Y. Wang, A. Polesskaya, I. Bieche, N. B. David, A. M. Gautreau

The paper shows that inactivating three negative regulators of cortical branched actin enhances migration persistence in human and zebrafish cells, with vimentin down-regulation contributing to the stable maintenance of this phenotype.

bioRxiv · May 13, 2023Cell Biology

PPP2R1A Regulates Migration Persistence through the WAVE Shell Complex

Y. Wang, G. Chiappetta, R. Guerois, S. Romero, M. Krause, C. Dessalles, A. Babataheri, A. I. Barakat, J. Vinh, A. Polesskaya, A. M. Gautreau

This study identifies PPP2R1A's role in migration persistence via the WAVE Shell Complex, showing its tumor suppressor function through actin regulation.

bioRxiv · Jun 2, 2022 · PreprintCell Biology

Restrained activation of CYFIP2-containing WAVE complexes controls membrane protrusions and cell migration

A. Polesskaya, A. Boutillon, S. Yang, Y. Wang, S. Romero, Y. Liu, M. Lavielle, N. Molinie, N. Rocques, A. Fokin, R. Guerois, B. Chen, N. B. David, A. M. Gautreau

The paper shows CYFIP2-containing WAVE complexes restrain RAC1 activation, affecting cell migration, and mutations in CYFIP2 can enhance its activity.

bioRxiv · Jul 2, 2020 · PreprintCell Biology