Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
J. James, A. I. Fokin, D. Y. Guschin, H. Wang, A. Polesskaya, S. N. Rubtsova, C. Le Clainche, P. Silberzan, A. M. Gautreau, S. Romero
This study shows that vinculin's interaction with Arp2/3 inhibits branched actin assembly, affecting cell migration and cell cycle progression in mammary epithelial cells.
bioRxiv · Oct 9, 2023 · PreprintCell Biology
A. I. Fokin, A. Boutillon, J. James, L. Courtois, S. Vacher, G. Simanov, Y. Wang, A. Polesskaya, I. Bieche, N. B. David, A. M. Gautreau
The paper shows that inactivating three negative regulators of cortical branched actin enhances migration persistence in human and zebrafish cells, with vimentin down-regulation contributing to the stable maintenance of this phenotype.
bioRxiv · May 13, 2023Cell Biology
R. Said, H. Wang, J. Pernier, H. Narassimprakash, S. Romero, A. M. Gautreau, R.-M. Mege, C. Le Clainche
This study investigates how α-catenin, vinculin, and VASP work together in a complex to regulate actin assembly during adherens junction formation.
bioRxiv · Dec 4, 2022 · PreprintBiochemistry
Y. Wang, G. Chiappetta, R. Guerois, S. Romero, M. Krause, C. Dessalles, A. Babataheri, A. I. Barakat, J. Vinh, A. Polesskaya, A. M. Gautreau
This study identifies PPP2R1A's role in migration persistence via the WAVE Shell Complex, showing its tumor suppressor function through actin regulation.
bioRxiv · Jun 2, 2022 · PreprintCell Biology
F. E. Fregoso, T. van Eeuwen, G. Simanov, G. Rebowski, M. Boczkowska, A. Zimmet, A. M. Gautreau, R. Dominguez
This study determines the cryo-EM structure of Arpin bound to Arp2/3 complex and identifies sequence differences in the C-helix that distinguish inhibition from activation.
bioRxiv · Oct 30, 2021Biochemistry
G. Simanov, I. Dang, A. I. Fokin, K. Oguievetskaia, V. Campanacci, J. Cherfils, A. M. Gautreau
This study identifies Arpin's interacting partners, showing it regulates migration persistence through two independent pathways involving Tankyrase and Arp2/3.
bioRxiv · Mar 16, 2021Cell Biology
A. Polesskaya, A. Boutillon, S. Yang, Y. Wang, S. Romero, Y. Liu, M. Lavielle, N. Molinie, N. Rocques, A. Fokin, R. Guerois, B. Chen, N. B. David, A. M. Gautreau
The paper shows CYFIP2-containing WAVE complexes restrain RAC1 activation, affecting cell migration, and mutations in CYFIP2 can enhance its activity.
bioRxiv · Jul 2, 2020 · PreprintCell Biology
A. I. Fokin, V. David, K. Oguievetskaia, E. Derivery, C. E. Stone, L. Cao, N. Rocques, N. Molinie, V. Henriot, M. Aumont-Nicaise, M. V. Hinckelmann, F. SAUDOU, C. Le Clainche, A. P. Carter, G. Romet-Lemonne, A. M. Gautreau
The paper shows that the WASH complex interacts with Dynactin and uncaps it, allowing the Arp1/11 minifilament to prime Arp2/3 complex-mediated actin branching at endosomes.
bioRxiv · May 29, 2020Cell Biology