J. von Frieling

A mitochondrial sirtuin shapes the intestinal microbiota by controlling lysozyme expression

This study shows that dSirt4 in Drosophila controls lysozyme expression in the intestine, altering microbiota composition and reducing lifespan.

Recurrent phases of strict protein limitation inhibit tumor growth and restore lifespan in a Drosophila intestinal cancer model

The paper shows that cyclic severe protein restriction in Drosophila reduces tumor growth, restores gut function, and extends lifespan without the harmful effects of continuous restriction.

A high-fat diet induces a microbiota-dependent increase in stem cell activity in the Drosophila intestine

This paper shows that a high-fat diet increases intestinal stem cell activity in Drosophila, dependent on microbiota and JNK signaling in enterocytes.

Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms