Author

R. Abramovich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. C. Villani· 1 shared A. Giannou· 1 shared A. Rehman· 1 shared A. Veillette· 1 shared D. Schmidt-Arras· 1 shared E. Elinav· 1 shared E. Galun· 1 shared E. Hajaj· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. C. Villani

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2 papers

Recent·Most cited

Peripheral sgp130-mediated trans-signaling blockade induces obesity and insulin resistance in mice via PPARα suppression

T. Lanton, O. Levkovitch-Siany, S. Udi, J. Tam, R. Abramovich, S. Perles, E. Williams, J. Rachmilewitz, U. Mor, E. Elinav, D. Schmidt-Arras, A. Rehman, P. Rosenstiel, A. Giannou, S. Huber, , J. H. Axelrod

This study shows that blocking peripheral sgp130-mediated trans-signaling in mice causes obesity and insulin resistance by suppressing PPARα.

bioRxiv · Sep 24, 2020 · PreprintPhysiology

SLAMF6 deficiency augments tumor killing and skews towards an effector phenotype revealing it as a new T cell checkpoint

E. Hajaj, G. Eisenberg, S. Klein, S. Frankenburg, S. Merims, I. Ben David, T. Eisenhaure, S. E. Henrickson, A. C. Villani, N. Hacohen, N. Abudi, R. Abramovich, J. E. Cohen, T. Peretz, A. Veillette, M. Lotem

This study shows that SLAMF6 deficiency enhances T cell tumor-killing ability and shifts T cells toward an effector phenotype, suggesting SLAMF6 as a new immune checkpoint.

bioRxiv · Oct 31, 2019Physiology