A. Ruggiero

Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

Determinants of precocious B-cell aging in European adolescences living with perinatally acquired HIV-1 after over 10 years of suppressive therapy

This study identifies factors associated with precocious B-cell aging in adolescents with perinatally acquired HIV on long-term suppressive therapy, linking them to immune dysfunction and reduced vaccine response.

European Vintage tomatoes galore: a result of farmers combinatorial assorting/swapping of a few diversity rich loci

The paper analyzes genetic diversity in European vintage tomatoes, finding low overall diversity but high selective pressure on few loci shaping morphological traits.

Hypertension drives microbial translocation and shifts in the fecal microbiome of non-human primates

This study shows hypertension in non-human primates leads to gut barrier dysfunction and microbial translocation, altering the gut microbiome.

On-off transition and ultrafast decay of amino acid luminescence driven by modulation of supramolecular packing

This study investigates amino acid luminescence in aggregated states, finding that supramolecular packing, not chemical properties, drives visible light emission and reversible optical transitions.

An engineered stable mini-protein to plug SARS-Cov2 Spikes

The paper engineers a stable mini-protein that binds to SARS-CoV-2 Spike protein's RBD to block ACE2 interaction, showing nanomolar affinity and potential as an antiviral tool.

Impact of Advanced Maternal Age on Physiologic Adaptations to Pregnancy in Vervet Monkeys

This study examines the effects of advanced maternal age on pregnancy adaptations in vervet monkeys, finding physiological changes similar to human AMA pregnancies.

DRT111/SFPS splicing factor controls ABA sensitivity in Arabidopsis seed development and germination

This study shows that DRT111/SFPS splicing factor regulates ABA sensitivity in Arabidopsis seed development and germination by controlling splicing of ABI3 and interacting with SF1 and SUA.

The spindle assembly checkpoint functions during early development in non-chordate embryos.

The paper evaluates SAC activation in early embryos of diverse metazoan species, finding two classes of embryos with or without SAC proficiency, and suggests SAC activity is default in metazoans, silenced in chordates.

The genome of the jellyfish Clytia hemisphaerica and the evolution of the cnidarian life-cycle

This study presents the genome of Clytia hemisphaerica and analyzes transcriptomes across its life-cycle stages, revealing gene expression patterns and evolutionary insights into cnidarian development.