O. Ashenberg

A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity

This paper creates a spatial cell atlas of neuroblastoma, revealing tumor heterogeneity through multi-omics data and identifying spatial compartmentalization and signaling patterns.

A cellular and spatial atlas of TP53-associated tissue remodeling in lung adenocarcinoma

This study constructs a multi-omic atlas of TP53-mutant lung adenocarcinoma tumors, revealing altered cellular identity, gene expression programs, and spatial interactions in the tumor microenvironment.

A single cell atlas of human and mouse white adipose tissue

This study creates single-cell atlases of human and mouse white adipose tissue, identifying cell types and their roles in metabolic disease across different body weights and diets.

Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

The paper develops a cross-tissue single-nucleus RNA-seq atlas to identify cell types and gene functions in health and disease.

Parental-fetal interplay of immune genes leads to intrauterine growth restriction

This study identifies a maternal-fetal immune interaction involving KIR2DL1 and HLA-C*05 that causes intrauterine growth restriction in a humanised mouse model.

Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors.

The paper uses single-cell RNA sequencing to analyze immature human thymocytes and identifies thymus seeding precursors and T-lineage developmental pathways.