Author

M. Shokhirev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Bautista· 1 shared A. Sakamoto· 1 shared A. Spigelman· 1 shared B. Cravatt· 1 shared C. R. Esteban· 1 shared D. Lazar· 1 shared D. Remillard· 1 shared E. Chin· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPhysiology

A. Bautista

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

F. Hatanaka, K. Suzuki, K. Shojima, J. Yu, Y. Takahashi, A. Sakamoto, J. Prieto, M. Shokhirev, C. R. Esteban, E. Nunez-Delicado, J. C. I. Belmonte

The paper combines gene supplementation and genome editing to treat spinal muscular atrophy in mice, showing long-term therapeutic benefits.

bioRxiv · Apr 6, 2023Bioengineering

Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways

J. Ostojic, T. Sonntag, N. Ngyen, J. M. Vaughan, M. Shokhirev, M. Montminy

This study shows CRTC3 regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways, with implications for melanoma treatment.

bioRxiv · Jul 14, 2020Cell Biology

An activity-guided map of electrophile-cysteine interactions in primary human immune cells

E. Vinogradova, D. Lazar, R. Suciu, Y. Wang, G. Bianco, Y. Yamashita, V. Crowley, D. Remillard, K. Lum, G. Simon, E. Kemper, M. Lazear, S. Yin, M. Blewett, M. Dix, , B. Cravatt

The paper maps electrophile-sensitive cysteines in primary human T cells and shows how electrophilic compounds affect T cell activation through cysteine modification.

bioRxiv · Oct 17, 2019 · PreprintImmunology

Aging of human endocrine pancreatic cell types is heterogeneous and sex-specific

R. Arrojo e Drigo, G. Erikson, S. Tyagi, J. Capitanio, J. Lyon, A. Spigelman, A. Bautista, J. E. Manning Fox, M. Shokhirev, P. MacDonald, M. Hetzer

This study analyzes age-related changes in human endocrine pancreatic cell types, finding sex-specific and cell-type-specific effects of aging on beta cell function and transcriptional profiles.

bioRxiv · Aug 8, 2019 · PreprintPhysiology