A. Takagi

An attenuated vaccinia vaccine encoding the SARS-CoV-2 spike protein elicits broad and durable immune responses, and protects cynomolgus macaques and human ACE2 transgenic mice from SARS-CoV-2 and its variants

This study develops a vaccinia-based vaccine encoding SARS-CoV-2 spike protein that induces broad and durable immunity, protecting against multiple variants in non-human primates and transgenic mice.

Identification of HLA-A*24:02-restricted CTL candidate epitopes derived from the non-structural polyprotein 1a of SARS-CoV-2 and analysis of their conservation using the mutation database of SARS-CoV-2 variants

This study identifies 22 HLA-A*24:02-restricted CTL epitopes from SARS-CoV-2 pp1a and finds 7 are conserved across variants, suggesting potential for improved vaccines.

An immunodominance hierarchy exists in CD8+ T cell responses to HLA-A*02:01-restricted epitopes identified from the non-structural polyprotein 1a of SARS-CoV-2.

This study identifies HLA-A*02:01-restricted CD8+ T cell epitopes from SARS-CoV-2's non-structural polyprotein 1a and finds an immunodominance hierarchy among them.