Author

G. J. de Bree

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

M. J. van Gils· 4 shared M. Poniman· 4 shared R. W. Sanders· 4 shared G. Kerster· 3 shared J. A. Burger· 3 shared K. van der Straten· 3 shared M. Claireaux· 3 shared T. G. Caniels· 3 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

M. J. van Gils

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Author profile →

5 papers

Recent·Most cited

Deep profiling of antigen-specific B cells from different pathogens identifies novel compartments in the IgG memory B cell and antibody-secreting cell lineages

M. Claireaux, G. Elias, G. Kerster, L. H. Kuijper, M. C. Duurland, A. G. Paul, J. A. Burger, M. Poniman, W. Olijhoek, N. de Jong, R. de Jongh, E. Wynberg, H. D. van Willigen, M. Prins, G. J. de Bree, , S. M. van Ham

The paper identifies novel stages in IgG memory B cell and antibody-secreting cell differentiation by analyzing antigen-specific B cells from different pathogens using high-dimensional flow cytometry.

bioRxiv · Dec 19, 2023 · PreprintImmunology

Broad SARS-CoV-2 Neutralization by Monoclonal and Bispecific Antibodies Derived from a Gamma-infected Individual

D. Guerra, T. Beaumont, L. Radic, G. Kerster, K. van der Straten, M. Yuan, J. L. Torres, W.-H. Lee, H. Liu, M. Poniman, I. Bontjer, J. A. Burger, M. Claireaux, T. G. Caniels, J. L. Snitselaar, , M. J. van Gils

This study identifies broadly neutralizing monoclonal and bispecific antibodies from a Gamma variant-infected individual that effectively neutralize multiple SARS-CoV-2 variants.

bioRxiv · Oct 14, 2022Immunology

IgG1 responses following SARS-CoV-2 infection are polyclonal and highly personalized, whereby each donor and each clone displays a distinct pattern of cross-reactivity against SARS-CoV-2 variants

D. M. H. van Rijswijck, A. Bondt, M. Hoek, K. van der Straten, T. G. Caniels, M. Poniman, D. Eggink, C. B. E. M. Reusken, G. J. de Bree, R. W. Sanders, M. van Gils, A. J. R. Heck

The paper analyzes IgG1 clonal responses to SARS-CoV-2 variants in infected donors, finding unique and polyclonal antibody repertoires with varying cross-reactivity across variants.

bioRxiv · Feb 24, 2022Immunology

A public antibody class recognizes a novel S2 epitope exposed on open conformations of SARS-CoV-2 spike

M. Claireaux, T. G. Caniels, M. de Gast, J. Han, D. Guerra, G. Kerster, B. D. van Schaik, A. Jongejan, A. I. Schriek, M. Grobben, P. J. Brouwer, K. van der Straten, Y. Aldon, J. Capella-Pujol, J. L. Snitselaar, , M. J. van Gils

The paper identifies a novel S2 epitope recognized by a public antibody class in SARS-CoV-2-reactive B cells, which becomes exposed on vaccine-optimized spike proteins.

bioRxiv · Dec 1, 2021Immunology

Infection and transmission of SARS-CoV-2 depends on heparan sulfate proteoglycans

M. Bermejo-Jambrina, J. Eder, T. M. Kaptein, J. L. van Hamme, L. C. Helgers, K. E. Vlaming, P. J. Brouwer, A. P. Vlaar, F. E. H. P. van Baarle, M. Spaargaren, G. J. de Bree, B. M. Nijmeijer, N. A. Kootstra, M. J. van Gils, R. W. Sanders, T. B. H. Geijtenbeek

This study identifies heparan sulfate proteoglycans as SARS-CoV-2 attachment receptors and shows that LMWH blocks infection and transmission.

bioRxiv · Aug 18, 2020Immunology