Author

M. Beyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Marcu· 1 shared A. Nelde· 1 shared A. Odainic· 1 shared A. Roers· 1 shared A. ten Brinke· 1 shared A.-M. Schaffer· 1 shared A.-S. Mägdefrau· 1 shared B. Steglich· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperImmunology

A. Marcu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BBSome-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue

K. Sieckmann, N. Winnerling, D. J. Silva Ribeiro, R. Kardinal, L. M. Steinheuer, G. Schermann, C. Klausen, N. Blank-Stein, J. Schulte-Schrepping, C. Osei-Sarpong, M. Becker, L. Bonaguro, M. Beyer, K. Thurley, H. May-Simera, , D. Wachten

This study shows that primary cilia dysfunction in Bbs8-/- mice reduces adipose stem cells and promotes fibrogenic progenitors via disrupted Hedgehog signaling, affecting adipogenesis and lipid uptake.

bioRxiv · Jan 25, 2024 · PreprintCell Biology

Single-cell analysis reveals dynamics of human B cell differentiation and identifies novel B and antibody-secreting cell intermediates

N. Verstegen, S. Pollastro, P.-P. Unger, C. Marsman, G. Elias, T. Jorritsma, M. Streutker, K. Bassler, K. Haendler, T. Rispens, J. Schultze, A. ten Brinke, M. Beyer, M. S. van Ham

The paper uses single-cell RNA sequencing to study human B cell differentiation, identifying novel intermediates and a germinal-center-like population in vitro.

bioRxiv · Oct 3, 2022Immunology

Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition

R. Winkler, A.-S. Mägdefrau, E.-M. Piskor, M. Kleemann, M. Beyer, K. Linke, L. Hansen, A.-M. Schaffer, M. E. Hoffmann, S. Poepsel, F. Heyd, P. Beli, T. Möröy, S. Mahboobi, O. H. Krämer, C. Kosan

This study shows that inhibiting HDAC6 with Marbostat-100 reduces MYC levels and prevents lymphomagenesis in a mouse model of MYC-induced B-cell lymphoma.

Oncogene · Sep 6, 2022Peer-reviewedCancer Biology

Suppression of systemic T cell immunity to viral infection during liver injury is prevented by inhibition of interferon and IL-10 signaling

P. C. Hackstein, J. Spitzer, K. Symeonidis, H. Horvatic, T. Bedke, B. Steglich, L. Assmus, A. Odainic, N. Kessler, S. Klein, M. Beyer, R. Schmithausen, E. Latz, C. Kurts, J. Trebicka, , Z. Abdullah

The paper shows that liver injury suppresses systemic T cell immunity to viral infection, which can be reversed by inhibiting interferon and IL-10 signaling in preclinical models and human patients.

bioRxiv · Jul 21, 2022 · PreprintImmunology

An innovative approach for HLA typing, molecular tumor testing and the validation of tumor exclusive antigens

M. Ghosh, L. Bichmann, J. Scheid, G. Gueler, H. Schuster, M. Di Marco, A. Marcu, M. Beyer, A. Nelde, L. K. Freudenmann, L. Muehlenbruch, M. W. Loeffler, O. Kohlbacher, H.-G. Rammensee, S. Stevanovic

The paper describes an innovative approach for HLA typing, molecular tumor testing, and validation of tumor-exclusive antigens but has been withdrawn by the authors.

bioRxiv · Jun 5, 2020 · PreprintImmunology