A. Thapa

Trichoderma afroharzianum T22 induces rhizobia and flavonoid-driven symbiosis to promote tolerance to alkaline stress in garden pea

This study shows Trichoderma afroharzianum T22 promotes garden pea tolerance to alkaline stress by inducing rhizobia and flavonoid-driven symbiosis to mitigate Fe deficiency.

Understanding inter-individual social networks in mixed-species bird flocks

This study constructs individual-level social networks in mixed-species bird flocks in the Eastern Himalaya, revealing differences in flock structure and mechanisms between two flocktypes.

Constitutively synergistic multiagent drug formulations targeting MERTK, FLT3, and BCL-2 for treatment of AML

The paper develops a nanoscale combination drug formulation targeting MERTK, FLT3, and BCL-2 to treat AML, showing improved synergistic responses in vitro and in patient samples.

Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling

This study identifies oxytocin as an intestinal hormone produced and secreted by enterocytes in response to secretin stimulation by L. reuteri.

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes

This study identifies TET2-driven 5hmc loss at GATA6 as a mechanism defining PDAC transcriptional subtypes and shows that TET2 stabilization with Metformin and Vitamin C reverses squamous-like tumor features.

Ataxin-7 and non-stop coordinate SCAR protein levels, subcellular localization, and actin cytoskeleton organization

Brief Freezing Steps Lead to Robust Immunofluorescence in Drosophila Larval Brains

The paper compares immunofluorescence techniques for Drosophila larval brains, finding that freezing improves staining without compromising structural integrity.