Author

A. Utsunomiya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

B. J. Y. Tan· 2 shared K. Sugata· 2 shared M. Tokunaga· 2 shared O. Reda· 2 shared Y. Satou· 2 shared E. Sueoka· 1 shared H. Katsuya· 1 shared H. Nakamura· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

B. J. Y. Tan

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2 papers

Recent·Most cited

Viral antigen mismatch affects antiviral T-cell response and may impair immunotherapeutic efficacy against ATL

K. Sugata, M. Takatori, O. Reda, B. J. Y. Tan, M. Tokunaga, T. Sato, M. Ueda, Y. Yamano, A. Utsunomiya, Y. Satou

This study shows that mismatch between viral antigen epitopes and T-cell responses in HTLV-1 infection may reduce immunotherapy effectiveness against ATL.

bioRxiv · Jan 25, 2024 · PreprintImmunology

Retrovirus-induced leukemia - hijack of T-cell activation mechanisms revealed by single-cell analysis

B. J. Y. Tan, K. Sugata, O. Reda, M. Matsuo, K. Uchiyama, P. Miyazato, V. Hahaut, M. Yamagishi, K. Uchimaru, Y. Suzuki, T. Ueno, H. Suzushima, H. Katsuya, M. Tokunaga, Y. Uchiyama, , Y. Satou

This study uses single-cell RNA-Seq and TCR-Seq to show HTLV-1-infected T-cells transition into highly activated ATL cells with Treg signatures and upregulated HLA class II, enabling immune evasion.

bioRxiv · Sep 1, 2021 · PreprintMicrobiology