Author

T. Mak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Bergonzini· 1 shared A. Ekblaw· 1 shared A. Tynan· 1 shared A. W. McClure· 1 shared A. Wakeham· 1 shared B. Canal· 1 shared C. Basier· 1 shared C. I. Kothe· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. Bergonzini

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Food Fermentation in Space Is Possible, Distinctive, and Beneficial

M. Coblentz, J. D. Evans, C. I. Kothe, T. Mak, N. Rodriguez Valeron, P. Chwalek, K. Wejendorp, S. Garg, L. Pless, S. Mak, P. M. Sorensen, L. J. Jahn, A. Ekblaw

This study fermented miso on the International Space Station and found it is possible, with unique microbial and sensory characteristics compared to Earth-based controls.

bioRxiv · Feb 23, 2024 · PreprintMicrobiology

Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase

C. Basier, S. Basu, R. Beale, B. Canal, V. H. Cowling, J. F. Curran, T. D. Deegan, J. F. Diffley, L. S. Drury, R. Fujisawa, M. Howell, K. Labib, C. T. Lim, T. Mak, A. W. McClure, , T. U. Zeisner

This study identifies four small molecule inhibitors of SARS-CoV-2 nsp14 RNA cap methyltransferase, with three showing synergy with remdesivir in antiviral assays.

bioRxiv · Apr 7, 2021Bioengineering

Influence of the microenvironment on the modulation of the host response by the typhoid toxin

O. C. Martin, D. Butter, E. Paparouna, S. D. Theodorou, M. M. Haykal, E. Boutet-Robinet, T. Tebaldi, A. Bergonzini, M. Lopez Chiloeches, A. Wakeham, M. Rhen, T. Mak, V. Gorgoulis, I. S. Pateras, T. Frisan

This study investigates how typhoid toxin modulates host immune responses in health and disease by inducing DNA damage and senescence, with effects dependent on the host's inflammatory state.

bioRxiv · Jun 4, 2020Immunology

Antibody responses to immunization require sensory neurons

A. Tynan, T. Tsaava, M. Gunasekaran, I. Snee, T. Mak, P. Olofsson, U. Andersson, S. S. Chavan, K. J. Tracey

This study shows that TRPV1-expressing sensory neurons are required for antibody responses to novel antigens and that stimulating these neurons enhances antibody production.

bioRxiv · Nov 30, 2019 · PreprintImmunology