Author

Alesa Hughson

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:rat· 3 Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abraham A. PalmeriD· 3 shared Alexander C. LamparelliiD· 3 shared Alexander F. GiletaiD· 3 shared Apurva S. ChitreiD· 3 shared Celine L. St. PierreiD· 3 shared Christopher P. KingiD· 3 shared Connor D. MartiniD· 3 shared Jordan A. Tripi· 3 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Abraham A. PalmerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RatXcan: A framework for cross-species integration of genome-wide association and gene expression data

Natasha Santhanam, Sandra Sanchez‐Roige, Sabrina Mi, Yanyu Liang, Apurva S. Chitre, Daniel B. Munro, Denghui Chen, Jianjun Gao, Angel Garcia-Martinez, Anthony M. George, Alexander F. Gileta, Wenyan Han, Katie Holl, Alesa Hughson, Christopher P. King, , Hae Kyung Im

RatXcan extends transcriptome-wide association studies to rats, enabling cross-species integration of GWAS and gene expression data to identify shared genetic mechanisms of complex traits.

PLoS Genetics · Mar 31, 2025Peer-reviewedGenomics

Exponential increase in QTL detection with increased sample size.

Apurva S. Chitre, Oksana Polesskaya, Daniel B. Munro, Riyan Cheng, Pejman Mohammadi, Katie Holl, Jianjun Gao, Hannah V. Bimschleger, Angel Garcia Martinez, Anthony M. George, Alexander F. Gileta, Aidan P. Horvath, Alesa Hughson, Keita Ishiwari, Christopher P. King, , Abraham A. Palmer

The paper simulates GWAS in rats to show that larger sample sizes lead to an exponential increase in the number of significant loci detected.

bioRxiv · Jan 27, 2023 · PreprintGenetics

Genome wide association study in 3,173 outbred rats identifies multiple loci for body weight, adiposity, and fasting glucose

Apurva S. Chitre, Oksana Polesskaya, Katie Holl, Jianjun Gao, Riyan Cheng, Hannah V. Bimschleger, Angel Garcia Martinez, Tony George, Alexander F. Gileta, Wenyan Han, Aidan P. Horvath, Alesa Hughson, Keita Ishiwari, Christopher P. King, Alexander C. Lamparelli, , Leah C. Solberg Woods

Obesity · Aug 29, 2020Peer-reviewedGenetics