Author

Alexander E. Brady

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandria Lydecker· 1 shared Brian D. RuddiD· 1 shared Dongwen WuiD· 1 shared Elliott J. Purser· 1 shared Hannah Fisk· 1 shared Khadija Kone· 1 shared Mandy J. McGeachyiD· 1 shared Norah L. SmithiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

Alexandria Lydecker

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Humanizing a CD28 signaling domain affects CD8 activation, exhaustion and stem-like precursors

Alexander E. Brady, Shankar K. Revu, Dongwen Wu, Hannah Fisk, Khadija Kone, Alexandria Lydecker, Elliott J. Purser, Norah L. Smith, Zachary T. Hilt, Sarah Woodyear, Sarah Caddy, Sébastien Gingras, Brian D. Rudd, Mandy J. McGeachy

A single amino acid substitution in CD28 enhances signaling, leading to increased CD8 activation and Tpex generation during viral infection, while accelerating exhaustion in chronic infection.

bioRxiv · Mar 10, 2025 · PreprintImmunology