Author

Sarah Caddy

Cornell UniversityORCID 0000-0002-9790-7420Unclaimed ORCID profile · follow to get notified of new preprints

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Sarah Caddy1 paper

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Sarah WoodyeariD· 3 shared T. Lonergan· 2 shared Abigail M. ReidiD· 1 shared Alexander E. Brady· 1 shared Alexandria Lydecker· 1 shared Alexis AE Peprah· 1 shared Ana Alice Pimenta-PereiraiD· 1 shared Brian D. RuddiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Sarah WoodyearORCID

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3 papers

Recent·Most cited

Quantifying maternal antibody transfer to colostrum and cord blood reveals virus-specific selectivity in dogs

Serena S. Teh, Lotta Henni Truyen, Sarah Woodyear, Jessica Palmeri, Ana Alice Pimenta-Pereira, Alexis AE Peprah, Ella Lanman, T. Lonergan, Abigail M. Reid, Soon Hon Cheong, Sarah Caddy

The paper quantifies maternal antibody transfer in dogs and finds virus-specific antibodies are preferentially transferred via colostrum.

Frontiers in Immunology · Jan 14, 2026Peer-reviewedImmunology

Humanizing a CD28 signaling domain affects CD8 activation, exhaustion and stem-like precursors

Alexander E. Brady, Shankar K. Revu, Dongwen Wu, Hannah Fisk, Khadija Kone, Alexandria Lydecker, Elliott J. Purser, Norah L. Smith, Zachary T. Hilt, Sarah Woodyear, Sarah Caddy, Sébastien Gingras, Brian D. Rudd, Mandy J. McGeachy

A single amino acid substitution in CD28 enhances signaling, leading to increased CD8 activation and Tpex generation during viral infection, while accelerating exhaustion in chronic infection.

bioRxiv · Mar 10, 2025 · PreprintImmunology

Mechanisms of maternal antibody interference to rotavirus vaccination

Tawny L. Chandler, Sarah Woodyear, Valerie Chen, T. Lonergan, Natalie Baker, Katherine Harcourt, Simon Clare, Faraz Ahmed, Sarah Caddy

This study investigates how maternal antibodies interfere with rotavirus vaccination in neonates using a mouse model, finding that vaccine clearance rather than FcγRIIB signaling or epitope masking is the main mechanism of interference.

bioRxiv · Feb 26, 2025 · PreprintImmunology