Author

Fabio Pastorino

Istituto Giannina GasliniORCID 0000-0002-8312-808XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Agostina Di PizioiD· 1 shared Alfonso Martínez AriasiD· 1 shared Angelo IannielliiD· 1 shared Anna BigasiD· 1 shared Antonio EspositoiD· 1 shared Ayona Johns· 1 shared Chun-Wai Wade SueniD· 1 shared Connor ByrneiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Agostina Di PizioORCID

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2 papers

Recent·Most cited

Targeted and efficient AAV therapy for neuroblastoma via direct capsid-antibody coupling

Mirko Luoni, Serena Gea Giannelli, Stefano Parracino, Francesca Morosi, Elisa Ventura, Agostina Di Pizio, Sharon Muggeo, Angelo Iannielli, Tamara Canu, Tommaso Russo, Antonio Esposito, Fabio Pastorino, Vania Broccoli

This paper develops AAV-STITCH, a method to target neuroblastoma cells using anti-GD2 ScFv coupled to AAV capsids, showing selective transduction and tumor suppression in mouse models.

bioRxiv · Nov 12, 2025 · PreprintBioengineering

Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

Denise Ragusa, Chun-Wai Wade Suen, Gabriel Torregrosa-Cortés, Fabio Pastorino, Ayona Johns, Ylenia Cicirò, Liza Dijkhuis, Susanne van den Brink, Michele Cilli, Connor Byrne, Giulia-Andreea Ionescu, Joana Cerveira, Kamil R. Kranc, Víctor Hernández-Hernández, Mirco Ponzoni, , Cristina Pina

This paper introduces a 3D hemogenic gastruloid model to study infant acute myeloid leukemia origins, showing MNX1-driven transformation of erythroid-myeloid progenitors.

eLife · Sep 11, 2025Peer-reviewedDevelopmental Biology