Author

B. Cabukusta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Neefjes· 2 shared A. A. de Waard· 1 shared A. A. Mulder· 1 shared A. Mulder· 1 shared A. Xagara· 1 shared D. M. Borras· 1 shared E. Stickel· 1 shared F. H. J. Claas· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

J. Neefjes

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Author profile →

3 papers

Recent·Most cited

The ORP9-ORP11 dimer promotes sphingomyelin synthesis

B. Cabukusta, S. Borst Pauwels, J. J. L. L. Akkermans, N. Blomberg, A. A. Mulder, R. I. Koning, M. Giera, J. Neefjes

The paper identifies the ORP9-ORP11 dimer as critical for sphingomyelin synthesis by exchanging phosphatidylserine and phosphatidylinositol-4-phosphate at ER-Golgi contact sites.

bioRxiv · Jun 2, 2023Cell Biology

CRISPR activation screening identifies VGLL3 and GATA2 as transcriptional regulators of PD-L1

R. H. Wijdeven, B. Cabukusta, X. Qiu, D. M. Borras, Y. Liang, J. J. Neefjes

The paper identifies VGLL3 and GATA2 as transcriptional regulators that upregulate PD-L1 expression through CRISPR activation screening and functional validation.

bioRxiv · Aug 18, 2021 · PreprintImmunology

The SPPL3-defined glycosphingolipid repertoire regulates immune responses by improving HLA class I access

M. L. M. Jongsma, M. Raaben, A. A. de Waard, T. Zhang, B. Cabukusta, R. Platzer, V. A. Blomen, A. Xagara, T. Verkerk, S. Bliss, L. Janssen, E. Stickel, S. Holst, R. Plomp, A. Mulder, , R. M. Spaapen

The paper identifies a glycosphingolipid (GSL) signature that inhibits HLA-I antigen presentation and shows its reversal by clinically approved drugs.

bioRxiv · Sep 26, 2020Immunology