Author

F. H. J. Claas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Mulder· 3 shared A. A. de Waard· 2 shared M. L. M. Jongsma· 2 shared R. M. Spaapen· 2 shared S. Bliss· 2 shared T. Verkerk· 2 shared A. H. de Ru· 1 shared A. Halenius· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

A. Mulder

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Author profile →

3 papers

Recent·Most cited

Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance

Y. D. Muller, L. M. R. Ferreira, E. Ronin, P. Ho, V. Nguyen, G. Faleo, Y. Zhou, K. Lee, K. K. Leung, N. Skartsis, A. M. Kaul, A. Mulder, F. H. J. Claas, J. A. Wells, J. A. Bluestone, Q. Tang

This paper develops an anti-HLA-A2 CAR for Tregs to induce transplant tolerance, showing they target HLA-A2-expressing grafts and suppress immune rejection.

Frontiers in Immunology · Sep 20, 2021Peer-reviewedImmunology

The SPPL3-defined glycosphingolipid repertoire regulates immune responses by improving HLA class I access

M. L. M. Jongsma, M. Raaben, A. A. de Waard, T. Zhang, B. Cabukusta, R. Platzer, V. A. Blomen, A. Xagara, T. Verkerk, S. Bliss, L. Janssen, E. Stickel, S. Holst, R. Plomp, A. Mulder, , R. M. Spaapen

The paper identifies a glycosphingolipid (GSL) signature that inhibits HLA-I antigen presentation and shows its reversal by clinically approved drugs.

bioRxiv · Sep 26, 2020Immunology

PAKC: A novel Panel of HLA class I Antigen presentation machinery Knockout Cells from the same genetic origin

A. A. de Waard, T. Verkerk, M. L. M. Jongsma, K. Hoefakker, S. Sethumadhavan, C. Gerke, S. Bliss, G. M. C. Janssen, A. H. de Ru, F. H. J. Claas, A. Mulder, R. Tampe, P. A. van Veelen, A. Halenius, R. M. Spaapen

The paper generates a panel of APM knockout cell lines to study HLA class I antigen presentation and its role in immune responses.

bioRxiv · Jan 24, 2020Immunology