Author

B. Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Cayota· 1 shared A. Korshunov· 1 shared B. Radlwimmer· 1 shared D. Hines· 1 shared E. L. Ivanova· 1 shared F. Gambaro· 1 shared H. Peterziel· 1 shared H.-K. Liu· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. Cayota

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Preliminary pharmacokinetics and in vivo studies indicate analgesic and stress mitigation effects of a novel NMDA receptor modulator

B. Costa, D. Hines, N. Phillip, S. C. Boehringer, R. Anandakrishnan, M. Council-Troche, J. L. Davis

This paper investigates the analgesic and stress-mitigating effects of CNS4, a novel NMDA receptor modulator, showing reduced stress-related behaviors and no cognitive side effects.

bioRxiv · Jun 22, 2024Pharmacology & Toxicology

A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies

B. Costa, M. N. Fletcher, P. Boskovic, E. L. Ivanova, T. Eisemann, S. Lohr, L. Bunse, M. Loewer, S. Burchard, A. Korshunov, H.-K. Liu, M. Platten, B. Radlwimmer, P. Angel, H. Peterziel

This study develops a glioblastoma cell line from a genetic mouse model that mimics human glioblastoma features, enabling preclinical testing of immunotherapies.

bioRxiv · Mar 16, 2020 · PreprintCancer Biology

Fragmentation of extracellular ribosomes and tRNAs shapes the extracellular RNAome

J. P. Tosar, M. Segovia, F. Gambaro, Y. Akiyama, P. Fagundez, B. Costa, T. Possi, M. Hill, P. Ivanov, A. Cayota

The paper develops RI-SEC-seq to analyze nonvesicular exRNAs, revealing extracellular ribosomes and tRNAs that resist degradation and act as damage-associated molecular patterns.

bioRxiv · Jan 29, 2020Cell Biology