Author

T. Eisemann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Peterziel· 2 shared P. Angel· 2 shared A. Korshunov· 1 shared B. Costa· 1 shared B. Radlwimmer· 1 shared C. Conrad· 1 shared E. L. Ivanova· 1 shared F. Allen· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

H. Peterziel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tankyrase interacts with the allosteric site of glucokinase and inhibits its glucose-sensing function in the beta cell

N.-W. Chi, T. Eisemann, T.-Y. J. Yeh, S. Roy, T. J. Chi, S. H. Lu, J. M. Pascal, O. Osborn

This study identifies tankyrase (TNKS) as a physiological inhibitor of glucokinase (GCK) in pancreatic beta cells by trapping it in an inactive conformation.

bioRxiv · Aug 8, 2021 · PreprintCell Biology

The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation

T. Eisemann, F. Allen, K. Lau, G. R. Shimamura, P. D. Jeffrey, F. M. Hughson

This paper presents the structure of the Vps45–Tlg2 SM–Qa-SNARE complex, showing Vps45 holds Tlg2 in an open conformation, distinct from the closed conformation seen in Munc18-1–syntaxin 1 complexes.

bioRxiv · Jul 1, 2020Cell Biology

A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies

B. Costa, M. N. Fletcher, P. Boskovic, E. L. Ivanova, T. Eisemann, S. Lohr, L. Bunse, M. Loewer, S. Burchard, A. Korshunov, H.-K. Liu, M. Platten, B. Radlwimmer, P. Angel, H. Peterziel

This study develops a glioblastoma cell line from a genetic mouse model that mimics human glioblastoma features, enabling preclinical testing of immunotherapies.

bioRxiv · Mar 16, 2020 · PreprintCancer Biology

Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics

T. G. Krieger, S. M. Tirier, J. Park, T. Eisemann, H. Peterziel, P. Angel, R. Eils, C. Conrad

This study uses human brain organoids and single-cell transcriptomics to model GBM invasion, identifying transcriptional changes and potential therapeutic targets.

bioRxiv · May 7, 2019Cancer Biology