Author

H.-K. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

C. Shao· 2 shared Y. Zhuo· 2 shared A. A. Acikgöz· 1 shared A. Korshunov· 1 shared A. Neuerburg· 1 shared A. Schulze· 1 shared B. Costa· 1 shared B. Radlwimmer· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

C. Shao

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs

C. Wang, M. Sun, C. Shao, L. Schlicker, Y. Zhuo, Y. Harim, T. Peng, W. Tian, N. stoeffler, M. Schneider, D. Helm, J.-P. Mallm, Y. Wu, A. Schulze, H.-K. LIU

This study characterizes human glioblastoma organoids using multi-omics analysis and identifies drug targets linked to glycerol lipid reprogramming.

bioRxiv · Jan 24, 2023 · PreprintCancer Biology

Dynamin-2 Phosphorylation as A Critical Regulatory Target of Bin1 and GSK3α for Endocytosis in Muscle

J. Laiman, J. Loh, W.-C. Tang, M.-C. Chuang, H.-K. Liu, B.-C. Chen, Y.-C. Chang, L.-M. Chuang, Y.-W. Liu

This study identifies Bin1 and GSK3α regulation of Dyn2 phosphorylation as critical for endocytosis in muscle, linking it to hereditary myopathy.

bioRxiv · Oct 11, 2021 · PreprintCell Biology

A novel neural stem cell-derived immunocompetent mouse model of glioblastoma for preclinical studies

B. Costa, M. N. Fletcher, P. Boskovic, E. L. Ivanova, T. Eisemann, S. Lohr, L. Bunse, M. Loewer, S. Burchard, A. Korshunov, H.-K. Liu, M. Platten, B. Radlwimmer, P. Angel, H. Peterziel

This study develops a glioblastoma cell line from a genetic mouse model that mimics human glioblastoma features, enabling preclinical testing of immunotherapies.

bioRxiv · Mar 16, 2020 · PreprintCancer Biology

Exponential Growth of Glioblastoma In Vivo Driven by Rapidly Dividing and Outwardly Migrating Cancer Stem Cells

L. Buchauer, M. A. Khan, Y. Zhuo, C. Shao, P. Zou, W. Feng, M. Qian, G. Bekki, C. Bunne, A. Neuerburg, A. A. Acikgöz, M. Tomaschko, Z. Zhu, H. Alter, K. Hartmann, , H.-K. Liu

This study identifies that glioblastoma grows exponentially due to symmetric divisions of brain tumor stem cells (BTSCs) accumulating at the tumor rim.

bioRxiv · Aug 5, 2019 · PreprintCancer Biology