Author

B. L. Worley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. J. Grossberg· 1 shared A. Q. Bartlett· 1 shared C.-W. Chen· 1 shared D.-H. Shin· 1 shared H. Mendez· 1 shared J. Dickie· 1 shared J. I. Warrick· 1 shared K. M. Aird· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. J. Grossberg

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2 papers

Recent·Most cited

IL-6/STAT3 signaling drives early-stage pancreatic cancer cachexia via suppressed ketogenesis

P. C. Arneson-Wissink, H. Mendez, K. Pelz, J. Dickie, A. Q. Bartlett, B. L. Worley, S. M. Krasnow, R. Eil, A. J. Grossberg

This study identifies IL-6/STAT3 signaling as a driver of early-stage pancreatic cancer cachexia by suppressing ketogenesis and lipid oxidation in the liver.

Journal of Cachexia, Sarcopenia and Muscle · Apr 17, 2024Peer-reviewedCancer Biology

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells.

Y. S. Kim, P. Gupta-Vallur, V. M. Jones, B. L. Worley, S. Shimko, D.-H. Shin, L. C. Crawford, C.-W. Chen, K. M. Aird, T. Abraham, T. G. Shepherd, J. I. Warrick, N. Y. Lee, R. Phaeton, K. Mythreye, N. Hempel

This study shows that SIRT3 activation is required for ovarian cancer cell survival and metastasis by regulating mitochondrial antioxidant defenses and metabolic changes during detachment.

bioRxiv · Jun 13, 2019Cancer Biology