Author

B. S. Padman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. Lazarou· 3 shared T. N. Nguyen· 3 shared E. Adriaenssens· 2 shared G. Khuu· 2 shared J. Sawa-Makarska· 2 shared M. Skulsuppaisarn· 2 shared S. Martens· 2 shared S. Shoebridge· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCell Biology

M. Lazarou

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD

E. Adriaenssens, T. N. Nguyen, J. Sawa-Makarska, G. Khuu, M. Schuschnig, S. Shoebridge, E. M. Watts, K. D. Csalyi, B. S. Padman, M. Lazarou, S. Martens

This study identifies NAP1 and SINTBAD as regulators of mitophagy, inhibiting OPTN-driven initiation while promoting NDP52-driven progression.

bioRxiv · Sep 25, 2023Cell Biology

Unconventional Initiation of PINK1/Parkin Mitophagy by Optineurin

T. N. Nguyen, J. Sawa-makarska, G. Khuu, W. K. Lam, E. Adriaenssens, D. Fracchiolla, S. Shoebridge, B. S. Padman, M. Skulsuppaisarn, R. S. J. Lindblom, S. Martens, M. Lazarou

This study identifies an unconventional mechanism by which OPTN initiates mitophagy through TBK1 and the class III phosphatidylinositol 3-kinase complex I, distinct from the FIP200-ULK1/2 pathway.

bioRxiv · Aug 14, 2022Cell Biology

Atg4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

T. N. Nguyen, B. S. Padman, S. Zellner, L. Uoselis, M. Skulsuppaisarn, C. Behrends, M. Lazarou

This study reveals that Atg4 family proteins drive autophagosome formation independently of Atg8 lipidation and protease activity, using AI-driven 3D electron microscopy.

bioRxiv · Dec 17, 2020Cell Biology