Author

M. Skulsuppaisarn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. Lazarou· 4 shared T. N. Nguyen· 3 shared B. S. Padman· 2 shared G. Khuu· 2 shared L. Uoselis· 2 shared A. Filipovska· 1 shared C. Behrends· 1 shared D. Fracchiolla· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersCell Biology

M. Lazarou

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Author profile →

4 papers

Recent·Most cited

Three-step docking by WIPI2, ATG16L1 and ATG3 delivers LC3 to the phagophore

S. Rao, L. M. Strong, X. Ren, M. Skulsuppaisarn, M. Lazarou, J. H. Hurley, G. Hummer

The paper identifies three sequential steps by which the ATG12-ATG5-ATG16L1 complex delivers LC3 to the phagophore via WIPI2, ATG16L1, and ATG3.

bioRxiv · Jul 17, 2023Cell Biology

Temporal landscape of mitochondrial proteostasis governed by the UPRmt

L. Uoselis, R. Lindblom, M. Skulsuppaisarn, G. Khuu, T. N. Nguyen, D. L. Rudler, A. Filipovska, R. B. Schittenhelm, M. Lazarou

This study develops MitoPQ, a functional proteomics framework, to analyze how the UPRmt maintains mitochondrial proteostasis during stress and identifies oxidative phosphorylation as a key target.

bioRxiv · Nov 30, 2022Cell Biology

Unconventional Initiation of PINK1/Parkin Mitophagy by Optineurin

T. N. Nguyen, J. Sawa-makarska, G. Khuu, W. K. Lam, E. Adriaenssens, D. Fracchiolla, S. Shoebridge, B. S. Padman, M. Skulsuppaisarn, R. S. J. Lindblom, S. Martens, M. Lazarou

This study identifies an unconventional mechanism by which OPTN initiates mitophagy through TBK1 and the class III phosphatidylinositol 3-kinase complex I, distinct from the FIP200-ULK1/2 pathway.

bioRxiv · Aug 14, 2022Cell Biology

Atg4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system

T. N. Nguyen, B. S. Padman, S. Zellner, L. Uoselis, M. Skulsuppaisarn, C. Behrends, M. Lazarou

This study reveals that Atg4 family proteins drive autophagosome formation independently of Atg8 lipidation and protease activity, using AI-driven 3D electron microscopy.

bioRxiv · Dec 17, 2020Cell Biology