Author

B. T. Layden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Physiology· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:metagenomics· 3 Organism:mouse· 3 Organism:human· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Sharma· 2 shared B. Wicksteed· 2 shared G. Navarro· 2 shared J. A. Gilbert· 2 shared L. R. Dugas· 2 shared M. Priyadarshini· 2 shared M. W. Khan· 2 shared A. Luke· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

A. Sharma

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Estrogen prevents age-dependent beige adipogenesis failure through NAMPT-controlled ER stress pathway

J. Park, R. Hu, S. Xiong, Y. Qian, A. S. El-Sabbagh, M. Ibrahim, Q. Song, G. Yan, Z. Song, A. M. Mahmoud, Y. He, B. T. Layden, J. Chen, S.-G. Ong, P. W. Xu, Y. Jiang

This study shows estrogen prevents age-related failure in beige adipogenesis by controlling ER stress via NAMPT, improving energy expenditure and glucose tolerance in mice.

bioRxiv · Aug 31, 2023 · PreprintPhysiology

Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study

G. Ecklu-Mensah, C. Choo-Kang, M. G. Maseng, S. Donato, P. Bovet, K. Bedu-Addo, J. Plange-Rhule, T. E. Forrester, E. V. Lambert, D. Rae, A. Luke, B. T. Layden, S. O'Keefe, J. A. Gilbert, L. R. Dugas

This study examines how gut microbiota, short chain fatty acids (SCFAs), and obesity vary by country of origin and adiposity in a large African-origin cohort, finding significant differences in microbial composition and SCFA levels across populations.

bioRxiv · Mar 21, 2023Microbiology

The hexokinase ''HKDC1'' interaction with the mitochondria is essential for hepatocellular carcinoma progression

M. W. Khan, A. Terry, M. Priyadarshini, G. Guzman, J. Cordoba-Chacon, I. Ben-Sahra, B. Wicksteed, B. T. Layden

This study shows that HKDC1's interaction with mitochondria is critical for HCC progression by altering metabolism and causing mitochondrial dysfunction.

bioRxiv · Nov 10, 2021 · PreprintCancer Biology

Gestational insulin resistance is mediated by the gut microbiome-indoleamine 2,3-dioxygenase axis

M. Priyadarshini, G. Navarro, D. Reiman, A. Sharma, K. Xu, K. Lednovich, C. R. Manzella, M. W. Khan, B. Wicksteed, G. E. Chlipala, B. Szynal, B. P. Bernabe, P. M. Maki, R. K. Gill, J. Gilbert, , B. T. Layden

This study identifies the gut microbiome-indoleamine 2,3-dioxygenase (IDO1) axis as a mediator of gestational insulin resistance in mice.

bioRxiv · Jul 21, 2021Physiology

Gut microbial features can predict host phenotype response to protein deficiency

G. Navarro, A. Sharma, L. R. Dugas, T. Forrester, J. A. Gilbert, B. T. Layden

The paper investigates how gut microbiota differences predict nitrogen balance and growth responses to protein deficiency in mice.

bioRxiv · Aug 22, 2018Physiology