B. Zhu

The paper develops PANINI-MIBI to analyze DNA, RNA, and protein in SIV-infected tissues, revealing IL10 upregulation and macrophage polarization linked to viral latency.

This study produces SARS-CoV-2 virus-like particles in insect cells for vaccine development and research.

This study identifies GajA as a nucleotide-regulated endonuclease from the Gabija bacterial defense system, which is inhibited by NTP and dNTP but activated during phage infection.

This study shows that A-to-I RNA editing in Xanthomonas oryzae enhances iron uptake by modifying the xfeA gene, improving bacterial competitiveness in iron-limited environments.

The paper shows that β-Amyloid peptides modulate the switching behavior of donor-acceptor Stenhouse adducts, reducing molecular switching rates and inhibiting aggregation.

This study shows that manganese depletion in Streptococcus sanguinis causes widespread transcriptomic changes, affecting multiple systems and growth, but no single factor fully explains the growth defect.

This study clones and expresses the pig ACE2 gene in a prokaryotic system, produces a polyclonal antibody, and confirms ACE2 expression across pig tissues.

This paper introduces a drug discovery platform called SPEED that uses epitope editing to screen small molecules for altering antibody-epitope interactions and validates its application for Aβ species.

This paper introduces subHMM, a hidden Markov model to estimate subclone regions, genotypes, and clonal proportions in tumor cells, applied to renal cell carcinoma data.

This study uses RNA-seq to analyze Xanthomonas oryzae pv. oryzicola's response to H2O2, revealing horizontal gene transfer's role in its oxidative stress response.

The paper shows that host sex and genotype influence the gut microbiome response to helminth infection in fish.

The paper introduces RpsA mutations Δ438A and D123A into M. tuberculosis to confirm their role in pyrazinamide resistance.

This study shows that Pseudomonas aeruginosa inhibits growth of Streptococcus species by producing siderophores that compete for iron.

This paper introduces the pencil method to detect oscillations in gene transcription, revealing new 12-hour oscillations and confirming biological independence of circadian rhythms.

This study identifies drugs that enhance pyrazinamide's anti-persister activity by screening a clinical drug library against M. tuberculosis cultures enriched with persisters.